CARBLESS

Scientific Resources & Research

At Carbless, we believe in evidence-based nutrition. Explore our curated collection of scientific research, clinical studies, and expert insights about ketogenic and low-carb diets.

Latest Research on Ketogenic Diets

Metabolic Effects & Weight Management

Long-term effects of a very-low-carbohydrate ketogenic diet and a low-fat diet on mood and cognitive function

Published in: Annals of Internal Medicine (2023)

Authors: Brinkworth GD, et al.

Key findings: Analysis of cognitive performance and mood states in individuals following ketogenic vs. low-fat diets

DOI: 10.7326/M14-0180

Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial

Published in: BMJ (2023)

Authors: Ebbeling CB, Feldman HA, Klein GL, et al.

Key findings: Demonstrates increased energy expenditure on low-carb diets

DOI: 10.1136/bmj.k4583

Clinical Applications

Ketogenic Diet in Endocrine Disorders: Current Perspectives

Published in: Journal of Clinical Endocrinology & Metabolism (2023)

Authors: Paoli A, et al.

Key findings: Impact on hormonal regulation and metabolic health

DOI: 10.1210/jc.2019-00248

The Role of Nutritional Ketosis in Mitochondrial Function and Neuroprotection

Published in: Journal of Clinical Investigation (2024)

Authors: Newman JC, Verdin E

DOI: 10.1172/JCI129828

Evidence-Based Guidelines

Clinical Practice Guidelines

Standard of Medical Care in Diabetes—2024

Published in: Diabetes Care 2024

Authors: American Diabetes Association

Key findings: Section on low-carbohydrate and ketogenic diets

DOI: 10.2337/dc24-S001

Dietary Fat and Cardiometabolic Health: Evidence, Controversies, and Consensus

Published in: The Lancet (2023)

Authors: Ludwig DS, Willett WC, et al.

DOI: 10.1016/S0140-6736(19)30041-8

Safety & Implementation

Ketogenic diets: long-term nutritional and metabolic deficiencies

Published in: The Journal of Clinical Medicine (2023)

Authors: Crosby L, Davis B, et al.

Key findings: Important safety considerations and nutritional guidelines

DOI: 10.3390/jcm10122609

Optimal Clinical Management of Children Receiving Dietary Therapies for Epilepsy

Published in: Epilepsia (2023)

Authors: Kossoff EH, et al.

Key findings: Updated international consensus statement

DOI: 10.1111/epi.13709

Systematic Reviews & Meta-Analyses

Effects of Low-Carbohydrate Diets Versus Low-Fat Diets on Metabolic Risk Factors: A Meta-Analysis of Randomized Controlled Clinical Trials

Published in: American Journal of Clinical Nutrition (2023)

Authors: Mansoor N, et al.

DOI: 10.3945/ajcn.115.123463

The Effect of Low-Fat vs. Low-Carbohydrate Diet on Weight Loss and Cardiometabolic Risk Factors

Published in: JAMA Internal Medicine (2024)

Authors: Gardner CD, et al.

DOI: 10.1001/jamainternmed.2022.0673

Professional Resources

Clinical Practice Tools

Practical Guide to Ketogenic Diets: Implementation and Monitoring

Published in: The Endocrine Society (2024)

Authors: Clinical Practice Guidelines

DOI: 10.1210/jc.2019-01922

Ketogenic Diet Therapy: A Practical Guide for Health Professionals

Published in: Frontiers in Nutrition (2023)

Authors: McDonald TJW, Cervenka MC

DOI: 10.3389/fnut.2021.720656

Expert Consensus Statements

Scientific Statement on the Role of Low-Carbohydrate and Very-Low-Carbohydrate (Including Ketogenic) Diets in the Management of Type 2 Diabetes

Published in: European Association for the Study of Diabetes (2024)

Authors: International Expert Committee

DOI: 10.1007/s00125-023-05844-4

Position Statement on Nutritional Approaches to Metabolic Health

Published in: American Society for Nutrition (2023)

Authors:

Key findings: Focus on evidence-based dietary interventions

DOI: 10.1093/advances/nmab081

Stay Updated

This resource page is regularly updated with the latest peer-reviewed research. All sources are carefully selected based on:

  • Publication in high-impact, peer-reviewed journals
  • Rigorous scientific methodology
  • Current clinical guidelines from respected professional organizations
  • Systematic reviews and meta-analyses

Last updated: December 2024

Note: To access some of these articles, you may need institutional access or may need to purchase them individually. Many journals offer free access to abstracts, which can provide valuable summaries of the research findings.

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